Conventionally, MRI scans of the brain are aligned differently from site to site, from subject to subject within a site, and during repeat scans for a single subject. Due to reliance upon manual judgment-based processes, alignment and prescription applications suffer from a high degree of variability between exam sessions. This variability increases the variation in the rescan process, making it less reliable and more problematic for precise side-by-side comparisons or computer-aided volumetric analysis. It also produces inconsistent alignment, which makes standard 2-D viewing protocols for Radiologists (film and PACS based) more complex and inefficient. AutoAlign™ was created specifically to solve this challenge, correcting for differences in patient positioning between scans.
AutoAlign™ is included in NeuroQuant® and cleared for marketing as a medical device by the US FDA [510(k) K061855]. It is available for nonexclusive licensing to MRI OEMs, and since 2004, has been included as an option in the intelligent workflow system of a major MRI system vendor.
AutoAlign™ corrects for differences in patient positioning between scans. The consistent anatomical alignment provided by use of AutoAlign™ during the MRI acquisition process can:
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